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Ann Plast Surg. 1988 Sep;21(3):273-5.

Topical minoxidil: its use in treatment of male pattern baldness.

Kulick MI.

Department of Surgery, University of California Medical School, San Francisco.

This review outlines the findings associated with topical minoxidil use. Approximately one-third of the treated patients will obtain terminal hair growth using a 2 to 3% solution twice a day. Patients should receive treatment for a minimum of six months to evaluate the drug’s efficacy. Factors associated with patients who obtained new hair growth include: a thinning versus absolute baldness, treatment initiated at a relatively younger age, and hair growth noted within three months. Following a positive growth response, there may be a reduction in new hair growth gained with minoxidil use for more than one year.  Stopping the medication is associated with an exacerbation of hair loss. Currently, patients with hypertension, cardiovascular disease, or any serious systemic illness should be excluded from therapy. Patients should be monitored every four to six months, or sooner with any complaints. Initial evaluation should include monitoring of the blood pressure, pulse, electrocardiogram and serum lipid determinations.

Clin Exp Dermatol. 2008 Aug;33(5):585-7. Epub 2008 Mar 18.

Failure to treat alopecia areata with photodynamic therapy.

Fernández-Guarino M, Harto A, García-Morales I, Pérez-García B, Arrazola JM, Jaén P.

We treated six patients with static alopecia areata (AA) with photodynamic therapy (PDT). All patients had received other treatment before starting PDT, but with no benefit. All previous treatments were stopped at least 3 months before beginning PDT, and no other treatment was given during the study period. PDT was used on only one of the affected areas, or if there was only one affected area, to only part of that area; untreated areas served as controls. For all patients methylaminolaevulinic acid was applied under occulsion 3 h after irradiation with red light at 630 nm (37 J/cm(2), 7.5 min). One session was carried out each month. Clinical and fluorescence photographs were taken with a digital camera connected to ultraviolet flashes, both before and after each treatment. None of the patients with AA of the scalp achieved complete hair regrowth, either in thetreated or the untreated areas. Two of the patients showed growth of some thin hair over < 10 of the treated area. The remaining patients had no change. However, the patient with AA of the beard experienced complete regrowth after four sessions. To our knowledge, this is the first case of AA treated with PDT in this location. It may be that AA of beard hair responds better to PDT, but further studies are necessary.

 Clin Dermatol. 2008 Jan-Feb;26(1):62-78.

Siddha medicine–background and principles and the application for skin diseases.

Thas JJ.

Friends of Siddha Medicine 78, Trivandrum Road, Tirunelveli, Tamil Nadu 627 002,
India.
Siddha medicine is one of the most ancient medical systems of India. Siddha is the mother medicine of ancient Tamils/Dravidians of peninsular South India. The word Siddha means established truth. The persons who were associated with establishing such a Siddha school of thought were known as Siddhars. They recorded their mystic findings in medicine, yoga, and astrology in Tamil. Fundamental Principles of Siddha include theories of Five Elements (Aimpootham), and Three Forces/Faults (Mukkuttram). The Eight Methods of Examination (Envakai
Thervukal) is used to determine diagnosis, etiology, treatment and prognosis. Siddha has safe herbal and herbo mineral treatment for psoriasis, eczema, alopecia, diabetic ulcer, warts, vitiligo, pemphigus, pompholyx, leprosy, and many more very common and rare diseases. Lifestyle modifications including diet are important.

Related Links

    Some Nigerian plants of dermatologic importance. [Int J Dermatol. 2007]

    The use and safety of non-allopathic Indian medicines. [Drug Saf. 2002]

    Utilization behaviour patterns of Siddha clinics in Salem, Tamil Nadu. [Geogr Med. 1989] PMID:2767433

    Ayurveda and gynecological disorders. [J Ethnopharmacol. 2005] PMID:15652289

    Ayurveda and yoga in cardiovascular diseases. [Cardiol Rev. 2005] PMID:15834238